News: Research

2024

Gagliardi Group helps unravel the mysteries of copper-catalyzed nitrogen coupling

February 1, 2024

Cu-Catalyzed N-N, O-O, and C-C Coupling. Two ways to tango!

In a recent study published in collaboration between UChicago and UW Madison, researchers have uncovered new insights into how nitrogen centers couple together under copper catalysis. Their work challenges conventional wisdom and opens new avenues in the field of chemical reactivity.


AI poisoning tool Nightshade received 250,000 downloads in 5 days

January 30, 2024

AI-generated image of a computer tower and monitor smoking

In a Venture Beat article, CS Prof. Ben Zhao comments on the fact that his lab's tool "Nightshade" has received 250,000 downloads in the five days since its release, saying that "the response is simply beyond anything we imagined."
 


Exploring 3D Paintbrush: An AI that colors with words

January 26, 2024

Selection of objects with 3D paintbrush details added

Using Cascaded Score Distillation, Dale Decatur and the 3DL lab create 3D Paintbrush: a tool that makes high-resolution 3D edits in localized regions of 3D objects.


Simulations show how HIV sneaks into the nucleus of the cell

January 26, 2024

A simulation of the pore of the nucleus of the cell. From left, an overhead view; center, a cutaway view; and at right, with an HIV capsid (shown in blue-green) embedded.

Chemist Gregory Voth and team assemble massive model of the nuclear pore complex and HIV-1 virus capsid.


University of Chicago professor, PhD students create tools to protect art from generative AI

January 25, 2024

Video still showing an AI interpretation of a Van Gogh painting

In an ABC 7 video, Prof. Ben Zhao discusses Nightshade, a tool that protects artwork from being mimicked by AI.


UChicago researchers form new dynamic bio interfaces to aid biosensing and treatment

January 23, 2024

Bozhi Tian

As their recent research in Nature Chemical Engineering demonstrates, the Bozhi Tian lab, led by graduate student Jiuyun Shi, has developed new interfaces that offer adaptability, precision, and targeted interactions with biological components, a discovery that could have significant implications for the future of healthcare.  


Nightshade, the free tool that ‘poisons’ AI models, is now available for artists to use

January 23, 2024

A hand pours a bottle of glowing purple liquid onto a keyboard of a vintage desktop PC displaying a pixelated purple skull and crossbones log amid flickering lines of static

Venture Beat article announces that "Nightshade" from the Computer Science Department's SAND Lab is now available for use.


UChicago, Caltech study suggests that physical processes can have hidden neural network-like abilities

January 18, 2024

a cell pattern

We tend to separate the brain and the muscle—the brain does the thinking; the muscle does the doing. But a new study shows how the molecules that build structures, i.e, the muscle, can themselves do both the thinking and the doing.


Final supernova results from Dark Energy Survey offer unique insights into expansion of universe

January 18, 2024

Dark Energy Survey telescope in Chile

In 1998, astrophysicists discovered that the universe is expanding at an accelerating rate, attributed to a mysterious entity called dark energy that makes up about 70% of our universe.

Now, 25 years after the initial discovery, the scientists working on the Dark Energy Survey have released the results of an analysis using the same technique to further probe the mysteries of dark energy and the expansion of the universe.


Scientists find an unusual star that hints at a new way stars can die

January 11, 2024

artist’s rendition of the explosion that generated an unusual star

Discovery by UChicago astrophysicists, including Alex Ji, may change our picture of how stars explode and elements are made.


Group from CS to present four papers at most prestigious international quantum conference

January 11, 2024

Bill Fefferman

Assistant Professor Bill Fefferman and his group are headed to Taipei to present four works on today’s major quantum topics at QIP’24: the largest and most prestigious quantum computing research conference in the world.


GJ 367b is another dead world orbiting a red dwarf, say astronomers

January 10, 2024

illustration of the exoplanet Gliese 367 b

A Phys.org article details a paper by Astro postdoctoral fellow Michael Zhang titled "GJ 367b is a dark, hot, airless sub-Earth."


Using electricity, scientists find promising new method of boosting chemical reactions

January 3, 2024

Anna Wuttig

Asst. Prof. Anna Wuttig and her team found a way to use electricity to boost a type of chemical reaction often used in synthesizing new candidates for pharmaceutical drugs, which may lay the foundation for greener chemistry.


Targeting “undruggable” proteins that drive cancer

January 3, 2024

Raymond Moellering

Cancers are often driven by proteins created by specific oncogenes. Drugs aimed at these proteins take advantage of their surface configurations to latch on and prevent them from interfering with cells, but some families of proteins lack pockets or crevices on their surfaces that the drugs can use. Attacking them is like climbing up a wall with no footholds. For decades, these proteins have been considered “undruggable,” but chemist Raymond Moellering is working to change that.


2023

UChicago scientists innovate ‘hook and slide’ method to improve drug discovery

December 20, 2023

Image of fish hooks hanging against white background

UChicago scientists have developed a new "hook and slide" method where they can insert atoms within an already existing carbon framework. The innovation comes from a paper recently published in Science, by Rui Zhang, a fifth-year graduate student with the Guangbin Dong Lab. This new strategy developed by Zhang, with assistance from undergraduate Tingting Yu, promises to optimize medicinal chemistry.

Image by Skrypnykov Dmytro/Shutterstock